query-c1d7f6d369fea92d8598480926c26b09
What compensatory mutations in FA core genes confer resistance to chemotherapeutic drugs (e.g. cisplatin)? select ?geneLabel ?variantLabel ?variant ?drugLabel ?cid ?diseaseLabel ?ref where { values ?hgnc {"FANCA" "FANCB" "FANCC" "FANCE" "FANCF" "FANCG" "FANCL" "FANCM" "FANCD2" "FANCI" "UBE2T" "BRCA2" "BRIP1" "PALB2" "RAD51C" "SLX4" "ERCC4" "RAD51" "BRCA1" "MAD2L2" "XRCC2" "RFWD3"} ?gene wdt:P353 ?hgnc . ?variant wdt:P3433 ?gene . ?variant p:P3355 ?s . ?s ps:P3355 ?drug . ?s prov:wasDerivedFrom/pr:P854 ?ref . ?drug wdt:P662 ?cid . ?s pq:P2175 ?disease . ?disease wdt:P279* wd:Q12078 . SERVICE wikibase:label { bd:serviceParam wikibase:language "en" } }
Use at
- https://query.wikidata.org/sparql
PREFIX wikibase: <http://wikiba.se/ontology#>
PREFIX wdt: <http://www.wikidata.org/prop/direct/>
PREFIX wd: <http://www.wikidata.org/entity/>
PREFIX ps: <http://www.wikidata.org/prop/statement/>
PREFIX prov: <http://www.w3.org/ns/prov#>
PREFIX pr: <http://www.wikidata.org/prop/reference/>
PREFIX pq: <http://www.wikidata.org/prop/qualifier/>
PREFIX p: <http://www.wikidata.org/prop/>
PREFIX bd: <http://www.bigdata.com/rdf#>
#What compensatory mutations in FA core genes confer resistance to chemotherapeutic drugs (e.g. cisplatin)?
select ?geneLabel ?variantLabel ?variant ?drugLabel ?cid ?diseaseLabel ?ref where {
values ?hgnc {"FANCA" "FANCB" "FANCC" "FANCE" "FANCF" "FANCG" "FANCL" "FANCM" "FANCD2" "FANCI" "UBE2T" "BRCA2" "BRIP1" "PALB2" "RAD51C" "SLX4" "ERCC4" "RAD51" "BRCA1" "MAD2L2" "XRCC2" "RFWD3"}
?gene wdt:P353 ?hgnc .
?variant wdt:P3433 ?gene .
?variant p:P3355 ?s .
?s ps:P3355 ?drug .
?s prov:wasDerivedFrom/pr:P854 ?ref .
?drug wdt:P662 ?cid .
?s pq:P2175 ?disease .
?disease wdt:P279* wd:Q12078 .
SERVICE wikibase:label { bd:serviceParam wikibase:language "en" }
}
Query found at
graph TD
classDef projected fill:lightgreen;
classDef literal fill:orange;
classDef iri fill:yellow;
v7("?cid"):::projected
v8("?disease")
v5("?drug")
v2("?gene")
v1("?hgnc")
v6("?ref"):::projected
v4("?s")
v3("?variant"):::projected
a1((" "))
c14(["en"]):::literal
c10(["wd:Q12078"]):::iri
c12(["bd:serviceParam"]):::iri
bind0[/VALUES ?hgnc/]
bind0-->v1
bind00(["FANCA"])
bind00 --> bind0
bind01(["FANCB"])
bind01 --> bind0
bind02(["FANCC"])
bind02 --> bind0
bind03(["FANCE"])
bind03 --> bind0
bind04(["FANCF"])
bind04 --> bind0
bind05(["FANCG"])
bind05 --> bind0
bind06(["FANCL"])
bind06 --> bind0
bind07(["FANCM"])
bind07 --> bind0
bind08(["FANCD2"])
bind08 --> bind0
bind09(["FANCI"])
bind09 --> bind0
bind010(["UBE2T"])
bind010 --> bind0
bind011(["BRCA2"])
bind011 --> bind0
bind012(["BRIP1"])
bind012 --> bind0
bind013(["PALB2"])
bind013 --> bind0
bind014(["RAD51C"])
bind014 --> bind0
bind015(["SLX4"])
bind015 --> bind0
bind016(["ERCC4"])
bind016 --> bind0
bind017(["RAD51"])
bind017 --> bind0
bind018(["BRCA1"])
bind018 --> bind0
bind019(["MAD2L2"])
bind019 --> bind0
bind020(["XRCC2"])
bind020 --> bind0
bind021(["RFWD3"])
bind021 --> bind0
v2 --"p:direct/P353"--> v1
v3 --"p:direct/P3433"--> v2
v3 --"p:P3355"--> v4
v4 --"p:statement/P3355"--> v5
v4 --"prov:wasDerivedFrom"--> a1
a1 --"p:reference/P854"--> v6
v5 --"p:direct/P662"--> v7
v4 --"p:qualifier/P2175"--> v8
v8 --"p:direct/P279"--> c10
subgraph s1["http://wikiba.se/ontology#label"]
style s1 stroke-width:4px;
c12 --"wikibase:language"--> c14
end